Administration National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine behavior research support non-u.s. gov't male Animal Knockout microscopy electron pmid:19577336 doi:10.1016/j.neurobiolaging.2009.05.017 sun-uk kim mei-hua jin dong-seok lee oral aging / physiology* antioxidants / administration & dosage creb-binding protein / genetics creb-binding protein / metabolism cognition / drug effects cognition / physiology* cyclic amp-dependent protein kinases / metabolism enzyme activation / drug effects enzyme activation / genetics extracellular signal-regulated map kinases / metabolism hippocampus / cytology* learning disabilities / diet therapy learning disabilities / genetics long-term potentiation / drug effects long-term potentiation / genetics malondialdehyde / metabolism maze learning / physiology transmission / methods mitochondria / pathology neurons / drug effects neurons / metabolism neurons / physiology* neurons / ultrastructure peroxiredoxins / deficiency peroxiredoxins / metabolism* protein carbonylation / drug effects reactive oxygen species vitamin e / administration & dosage