Resistance to respiratory syncytial virus (RSV) challenge induced by infection with a vaccinia virus recombinant expressing the RSV M2 protein (Vac-M2) is mediated by CD8+ T cells, while that induced by Vac-F or Vac-G recombinants is mediated by antibodies.
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Resistance to respiratory syncytial virus (RSV) challenge induced by infection with a vaccinia virus recombinant expressing the RSV M2 protein (Vac-M2) is mediated by CD8+ T cells, while that induced by Vac-F or Vac-G recombinants is mediated by antibodies.

M Connors, A B Kulkarni, P L Collins, C Y Firestone, K L Holmes, H C Morse, 3rd, B R Murphy;M Connors;A B Kulkarni;P L Collins;C Y Firestone;K L Holmes;H C Morse, 3rd;B R Murphy;
Journal of Virology 1992 Vol. 66 pp. 1277-
178
murphy1992journalresistance

Abstract

It was previously demonstrated that the vaccinia virus recombinants expressing the respiratory syncytial virus (RSV) F, G, or M2 (also designated as 22K) protein (Vac-F, Vac-G, or Vac-M2, respectively) induced almost complete resistance to RSV challenge ...

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