Intracellular activity of azithromycin against bacterial enteric pathogens
Abstract
Azithromycin, a new azalide antibiotic, is active in vitro against a variety of enteric bacterial pathogens. Since it is concentrated inside human neutrophils and other cells, it might be particularly useful in the treatment of infections caused by enteropathogens that invade host tissues. The intra …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Comparative Study
microbial sensitivity tests
diarrhea / microbiology
pmid:7810998
pmc284662
doi:10.1128/aac.38.9.1915
r m rakita
k jacques-palaz
b e murray
azithromycin / blood
azithromycin / pharmacokinetics
azithromycin / pharmacology*
cefotaxime / blood
cefotaxime / pharmacokinetics
cefotaxime / pharmacology
enterobacteriaceae / drug effects*
enterobacteriaceae / immunology
erythromycin / blood
erythromycin / pharmacokinetics
erythromycin / pharmacology
escherichia coli / classification
escherichia coli / drug effects*
escherichia coli / immunology
intestines / microbiology
intracellular fluid / metabolism
intracellular fluid / microbiology
neutrophils / metabolism
neutrophils / physiology
phagocytosis
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111329
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