Porcine antiviral activity is increased by CRISPRa-SAM system

Porcine antiviral activity is increased by CRISPRa-SAM system

Jiang J;Sun Y;Xiao R;Wai K;Ahmad MJ;Khan FA;Zhou H;Li Z;Zhang Y;Zhou A;Zhang S;;
Bioscience reports 2019 Vol. 39 pp. -
302
j2019bioscienceporcine

Abstract

Clustered Regularly Interspaced Short Palindromic Repeat activation-synergistic activation mediator system (CRISPRa-SAM) has been efficiently used to up-regulate the targeted genes in human and mouse. But it is not known whether the CRISPRa-SAM system can be used against porcine disease because its …

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