National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine reproducibility of results adult female male adolescent aged middle aged Child Infant Comparative Study Prospective Studies preschool 80 and over Antigens sensitivity and specificity Cohort Studies pneumococcal / diagnosis* bacterial typing techniques meningitis bacterial / urine* false positive reactions pmid:12729992 doi:10.1016/s0732-8893(02)00548-5 zmira samra haim shmuely josef ben-ari bacterial / analysis* false negative reactions immunoassay / methods pneumococcal / cerebrospinal fluid streptococcus pneumoniae / immunology*