PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro
Abstract
The process of adipogenesis is known to involve the interplay of several transcription factors. Activation of one of these factors, the nuclear hormone receptor PPAR gamma, is known to promote fat cell differentiation in vitro. Whether PPAR gamma is required for this process in vivo has remained an …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
RNA
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
female
male
P.H.S.
Receptors
Chimera
Knockout
pmid:10549292
doi:10.1016/s1097-2765(00)80211-7
e d rosen
p sarraf
r m mortensen
adipose tissue / growth & development*
cell differentiation / genetics*
gene dosage
gene targeting / methods
glucose / metabolism
in situ hybridization
antisense
messenger / metabolism
cytoplasmic and nuclear / genetics*
cytoplasmic and nuclear / metabolism
sebaceous glands / cytology
skin / cytology
stem cells / metabolism
transcription factors / genetics*
transcription factors / metabolism
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