Evaluation of the protective efficacy of reshaped human monoclonal antibody RSHZ19 against respiratory syncytial virus in cotton rats

Evaluation of the protective efficacy of reshaped human monoclonal antibody RSHZ19 against respiratory syncytial virus in cotton rats

Wyde PR;Moore DK;Hepburn T;Silverman CL;Porter TG;Gross M;Taylor G;Demuth SG;Dillon SB;;
Pediatric research 1995 Vol. 38 pp. -
427
pr1995pediatricevaluation

Abstract

Reshaped human MAb RSHZ19, which is specific for the surface fusion protein of respiratory syncytial virus (RSV) is in clinical development for the prevention and treatment of RSV-induced disease in human infants. The current studies profile lung virus clearance and evaluate lung histopathology in M …

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