Genetically determined susceptibility to mycobacterial infection
Abstract
Individuals with impaired cell mediated immunity exhibit increased susceptibility to infections caused by poorly pathogenic mycobacteria (non-tuberculous mycobacteria and BCG), as well as salmonella species. However, these infections may also occur in a disseminated, fatal form, sometimes with a fam …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
humans
pubmed abstract
nih
national institutes of health
national library of medicine
Receptors
Genotype
mutation
pmid:18326015
doi:10.1136/jcp.2007.051201
s y patel
r doffinger
d s kumararatne
cytokines / immunology*
genetic predisposition to disease*
interferon-gamma / genetics
interleukin-12 / deficiency
interleukin-12 / immunology
interleukin-12 subunit p40 / deficiency
interleukin-12 subunit p40 / genetics
interleukin-23 / deficiency
interleukin-23 / immunology
mycobacterium infections
nontuberculous / genetics*
nontuberculous / immunology
mycobacterium bovis / immunology
interferon / genetics
interleukin-12 / genetics
stat1 transcription factor / deficiency
stat1 transcription factor / genetics
tyk2 kinase / genetics
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110512
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