Activated NLR family pyrin domain containing 3 (NLRP3) inflammasome in keratinocytes promotes cutaneous T-cell response in patients with vitiligo

Activated NLR family pyrin domain containing 3 (NLRP3) inflammasome in keratinocytes promotes cutaneous T-cell response in patients with vitiligo

Li S;Kang P;Zhang W;Jian Z;Zhang Q;Yi X;Guo S;Guo W;Shi Q;Li B;He Y;Song P;Liu L;Li K;Wang G;Gao T;Li C;;
the journal of allergy and clinical immunology 2020 Vol. 145 pp. -
391
s2020theactivated

Abstract

Oxidative stress-induced NLRP3 inflammasome activation in keratinocytes promotes the cutaneous T-cell response, which could be targeted for the treatment of vitiligo.

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