C/EBPβ, When Expressed from the C/ebpα Gene Locus, Can Functionally Replace C/EBPα in Liver but Not in Adipose Tissue

C/EBPβ, When Expressed from the C/ebpα Gene Locus, Can Functionally Replace C/EBPα in Liver but Not in Adipose Tissue

Shih-Shun Chen, Jin-Feng Chen, Peter F. Johnson, Vijayakumar Muppala, Ying-Hue Lee;Shih-Shun Chen;Jin-Feng Chen;Peter F. Johnson;Vijayakumar Muppala;Ying-Hue Lee;
molecular and cellular biology 2000 Vol. 20 pp. 7292-
197
lee2000molecularc/ebpβ,

Abstract

Knockout of C/EBPα causes a severe loss of liver function and, subsequently, neonatal lethality in mice. By using a gene replacement approach, we generated a new C/EBPα-null mouse strain in which C/EBPβ, in addition to its own ...

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10.1128/mcb.20.19.7292-7299.2000
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