Polycystic ovarian syndrome: evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to inhibition by estradiol and progesterone
Abstract
Polycystic ovarian syndrome (PCOS) is a complex disorder with multiple abnormalities, including hyperandrogenism, ovulatory dysfunction, and altered gonadotropin secretion. The majority of patients have elevated LH levels in plasma and a persistent rapid frequency of LH (GnRH) pulse secretion, the m …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
adult
female
luteinizing hormone / blood
polycystic ovary syndrome / physiopathology*
P.H.S.
Clinical Trial
body mass index
reference values
pmid:11095431
doi:10.1210/jcem.85.11.6992
c a eagleson
m b gingrich
j c marshall
17-alpha-hydroxyprogesterone / blood
activity cycles
androgen antagonists / pharmacology
androgen antagonists / therapeutic use*
dehydroepiandrosterone sulfate / blood
estradiol / blood
flutamide / pharmacology
flutamide / therapeutic use*
follicle stimulating hormone / blood
follicle stimulating hormone / metabolism
luteinizing hormone / metabolism*
polycystic ovary syndrome / blood
polycystic ovary syndrome / drug therapy*
thyroxine / blood
Access
Citation
ID:
110239
References
Blockchain Verification
Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
110239
Unique Identifier:
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
Creates 1,000,000 NFT tokens for this article
Token Features:
- ERC-1155 Standard NFT
- 1 Million Supply per Article
- Transferable via MetaMask
- Permanent Blockchain Record
Scan with Saymatik Web3.0 Wallet