Coordinated Regulation of PPARγ Expression and Activity through Control of Chromatin Structure in Adipogenesis and Obesity
Eeckhoute J;Oger F;Staels B;Lefebvre P;;
ppar research2012Vol. 2012pp. -
396
j2012pparcoordinated
Abstract
The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is required for differentiation and function of mature adipocytes. Its expression is induced during adipogenesis where it plays a key role in establishing the transcriptome of terminally differentiated white fat cells. Her …