RuCl3 · nH2O as Catalyst for Diastereoselective Direct Aldol Reaction: An Efficient Route to Hormone Steroid Derivatives

RuCl3 · nH2O as Catalyst for Diastereoselective Direct Aldol Reaction: An Efficient Route to Hormone Steroid Derivatives

Tabatabaeian, Khalil;Keshavarz, Elahe;Mamaghani, Manouchehr;Mahmoodi, Nosrat O.;Tabatabaeian, Khalil;Keshavarz, Elahe;Mamaghani, Manouchehr;Mahmoodi, Nosrat O.;
organic chemistry international 2010 Vol. 2011
226
khalil2010rucl3nh2oorganic

Abstract

RuIII-catalyzed regio- and diastereoselective direct aldol reaction of progesterone with aromatic aldehydes has been developed in good yields (58–78%). Advantages of this method include catalytic efficiency, short reaction times, and ease of operation and workup.

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