Performance of oropharyngeal swab testing compared to nasopharyngeal swab testing for diagnosis of COVID-19 -United States, January-February 2020.
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Performance of oropharyngeal swab testing compared to nasopharyngeal swab testing for diagnosis of COVID-19 -United States, January-February 2020.

Patel, Monita R;Carroll, Darin;Ussery, Emily;Whitham, Hilary;Elkins, Christopher A;Noble-Wang, Judith;Rasheed, James Kamile;Lu, Xioayan;Lindstrom, Stephen;Bowen, Virginia;Waller, Jessica;Armstrong, Gregory;Gerber, Susan;Brooks, John T;
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2020
201
patel2020performanceclinical

Abstract

Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days since illness onset, CDC real-time RT-PCR SARS-CoV-2 assay diagnostic results were 95.2% concordant. However, NP swab Ct values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect amount of SARS-CoV-2.

Keywords

testing coronavirus nasopharyngeal sars-cov-2 cycle threshold values oropharyngeal

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