Brain insulin sensitivity is linked to adiposity and body fat distribution
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Brain insulin sensitivity is linked to adiposity and body fat distribution

Kullmann, Stephanie;Valenta, Vera;Wagner, Robert;Tschritter, Otto;Machann, Jürgen;Häring, Hans-Ulrich;Preissl, Hubert;Fritsche, Andreas;Heni, Martin;
Nature communications 2020 Vol. 11 pp. 1-6
204
kullmann2020brainnature

Abstract

Brain insulin action regulates eating behavior and whole-body energy fluxes, however the impact of brain insulin resistance on long-term weight and body fat composition is unknown. Here, the authors show that high brain insulin sensitivity is linked to weight loss during lifestyle intervention and associates with a favorable body fat distribution.

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