Loneliness, a widespread global public health concern, has far-reaching implications for mental and physical well-being, as well as economic productivity. It also increases the risk of life-threatening conditions. This study investigated the loneliness in social relationships of the SHS Grade 11 students of Colegio de San Antonio de Padua and employed a quantitative, comparative design in comparing the loneliness levels between the two groups, male and female. The study reported the means of loneliness scores for both males and females. The analysis showed that males (M = 2.31) experienced slightly higher levels of loneliness than females (M = 2.30). However, the result does not yield a significant difference, as the mean difference [standardized mean difference (SMD) = 0.586, P >.541] between the two groups was not substantial enough to reject the null hypothesis. Based on the findings and conclusion, it was recommended that teachers, academic institutions, and administrators implement a program regarding the prevalence of loneliness in the context of social relationships so students do not undervalue the feelings of loneliness.
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