Abstract
The incorporation of gold nanoparticles (AuNPs) into skincare formulations has garnered significant interest due to their unique physicochemical properties and potential dermatological benefits. AuNPs exhibit antioxidant, anti-inflammatory, and antimicrobial effects, making them promising candidates for anti-aging, brightening, and therapeutic skincare applications. Their nanoscale size enhances transdermal penetration, facilitating improved delivery of active ingredients. Additionally, AuNPs may stimulate collagen synthesis and neutralize free radicals, contributing to skin rejuvenation. However, concerns regarding long-term safety, potential cytotoxicity, and skin irritation necessitate further research. This review explores the mechanisms, benefits, and risks of AuNPs in topical formulations, highlighting current applications in cosmeceuticals while addressing critical safety considerations for future advancements.