Facilitated binding of TATA-binding protein to nucleosomal DNA
Abstract
BINDING of the TATA-binding protein (TBP) to the TATA box is required for transcription from many eukaryotic promoters in gene expression. Regulation of this binding is therefore likely to be an important determinant of promoter activity. Incorporation of the TATA sequence into nucleosomes dramatica …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
P.H.S.
DNA-Binding Proteins / metabolism*
Transcription Factors / metabolism*
recombinant proteins
hela cells
protein conformation
protein binding
saccharomyces cerevisiae / genetics
adenosine triphosphatases
h kwon
a n imbalzano
dna helicases
nuclear proteins*
nucleosomes / metabolism*
saccharomyces cerevisiae / metabolism
tata-box binding protein
saccharomyces cerevisiae proteins
pmid:8047170
doi:10.1038/370481a0
r e kingston
dna / metabolism*
tata box*
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274198
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