Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence

Briggs MR;Yokoyama C;Wang X;Brown MS;Goldstein JL;;
The Journal of biological chemistry 1993 Vol. 268 pp. -
300
mr1993thenuclear

Abstract

The current paper reports the identification of a protein in rat liver nuclei that binds to the sterol regulatory element (SRE-1) in the promoter of the gene for the low density lipoprotein receptor. The 10-base pair SRE-1 is embedded within a 16-base pair sequence designated Repeat 2 located immedi …

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