Formation of regulator/target gene relationships during evolution
Schlake T;Schorpp M;Boehm T;;
Gene2000Vol. 256pp. -
240
t2000geneformation
Abstract
The Foxn1-like forkhead/winged-helix transcription factor genes have been maintained in single copy throughout chordate evolution. Among other functions, Foxn1 (formerly known as Whn) regulates the expression of hair keratin genes in the hair follicle, which represents an evolutionarily novel organ …