In vivo requirements for rDNA chromosome condensation reveal two cell-cycle-regulated pathways for mitotic chromosome folding
Abstract
Chromosome condensation plays an essential role in the maintenance of genetic integrity. Using genetic, cell biological, and biochemical approaches, we distinguish two cell-cycle-regulated pathways for chromosome condensation in budding yeast. From G(2) to metaphase, we show that the condensation of …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
conserved sequence
DNA
Genotype
ribosomal / genetics*
chromosomes
phosphorylation
cell cycle proteins / genetics
dna-binding proteins / metabolism
fungal / genetics
saccharomyces cerevisiae / genetics*
cell cycle proteins / metabolism
saccharomyces cerevisiae proteins / metabolism
multiprotein complexes
mitosis
protein kinases / metabolism
aurora kinases
xenopus proteins
fungal / genetics*
adenosine triphosphatases / metabolism
protein kinases / genetics
protein-serine-threonine kinases
saccharomyces cerevisiae / cytology
cell cycle / genetics*
pmid:14701879
pmc314280
doi:10.1101/gad.1150404
brigitte d lavoie
eileen hogan
doug koshland
fungal / ultrastructure
metaphase
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Citation
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271555
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