Survival of Aspergillus fumigatus in serum involves removal of iron from transferrin: the role of siderophores
Abstract
Aspergillus fumigatus is a filamentous fungus which can cause invasive disease in immunocompromised individuals. A. fumigatus can grow in medium containing up to 80% human serum, despite very low concentrations of free iron. The purpose of this study was to determine the mechanism by which A. fumiga …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
in vitro techniques
culture media
virulence
dialysis
iron / metabolism*
siderophores / metabolism*
pmid:14977945
pmc356059
doi:10.1128/iai.72.3.1402-1408.2004
a h t hissen
j m t chow
m m moore
aspergillosis / etiology
aspergillus fumigatus / growth & development
aspergillus fumigatus / metabolism*
aspergillus fumigatus / pathogenicity*
transferrin / metabolism*
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270060
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