Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes
Abstract
Onset of Type 2 diabetes occurs when the pancreatic beta-cell fails to adapt to the increased insulin demand caused by insulin resistance. Morphological and therapeutic intervention studies have uncovered an inflammatory process in islets of patients with Type 2 diabetes characterized by the presenc …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
diabetes mellitus
inflammation / immunology
cytokines / immunology
type 2 / immunology
pmid:19996363
doi:10.1152/physiol.00032.2009
marc y donath
marianne böni-schnetzler
jan a ehses
type 2 / pathology*
inflammation / pathology
insulin resistance / immunology
insulin-secreting cells / immunology
insulin-secreting cells / pathology*
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269494
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