National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female male adolescent aged middle aged Comparative Study 80 and over Evaluation Study Polymerase Chain Reaction / methods* pneumonia pneumococcal / diagnosis* streptococcus pneumoniae / genetics streptococcus pneumoniae / isolation & purification* community-acquired infections / microbiology* community-acquired infections / diagnosis* sputum / microbiology* pharynx / microbiology blood / microbiology pneumococcal / microbiology* streptococcus pneumoniae / growth & development urine / microbiology pmid:18036762 doi:10.1016/j.diagmicrobio.2007.10.011 niclas johansson mats kalin jonas hedlund