The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH

The respiratory burst of phagocytic cells is associated with a rise in vacuolar pH

Segal AW;Geisow M;Garcia R;Harper A;Miller R;;
Nature 1981 Vol. 290 pp. -
249
aw1981naturethe

Abstract

Neutrophil leukocytes are the body's major defence against bacteria, which they phagocytose and kill. It has been found that phagocytosis and killing are accompanied by a dramatic rise in non-mitochondrial respiration; and that the efficiency of killing is impaired in the absence of oxygen. It is al …

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