Effects of androgens on adipocyte differentiation and adipose tissue explant metabolism in men and women
Abstract
Androgens slightly decreased HR-LPL activity in adipose tissue organ cultures, but markedly inhibited adipogenesis in SC and OM primary preadipocyte cultures in both sexes. Androgenic effects on adipose tissue in men vs. women may not differ in terms of direction but in the magnitude of their negati …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
adult
female
male
aged
middle aged
Apoptosis / drug effects
Cells
Cultured
polymerase chain reaction
Adipocytes / drug effects
Adipose Tissue / metabolism*
organ culture techniques
adipocytes / cytology*
blotting
western
androgens / pharmacology*
testosterone / pharmacology
karine blouin
andré tchernof
dihydrotestosterone / pharmacology
pmid:19500113
doi:10.1111/j.1365-2265.2009.03645.x
mélanie nadeau
adipose tissue / drug effects*
cell differentiation / drug effects*
glycerolphosphate dehydrogenase / genetics
glycerolphosphate dehydrogenase / metabolism
lipid metabolism / drug effects
metribolone / pharmacology
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267906
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