National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't adult female male adolescent aged middle aged young adult randomized controlled trials as topic 80 and over Antibodies Monoclonal Brian G Feagan time factors patient reported outcome measures placebos / administration & dosage jean-frédéric colombel karen lasch clinical trials phase iii as topic pmid:29857145 doi:10.1016/j.cgh.2018.05.026 humanized / administration & dosage* gastrointestinal agents / administration & dosage* inflammatory bowel diseases / drug therapy* inflammatory bowel diseases / pathology*