National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't amino acid sequence conserved sequence genetic* Nuclear Proteins / metabolism* Receptors Cytoplasmic and Nuclear / metabolism* Transcription Factors / metabolism* ligands transcription transfection nuclear proteins / genetics protein structure dna / metabolism recombinant fusion proteins / metabolism secondary adaptor proteins signal transducing pmid:9192902 doi:10.1038/42750 d m heery e kalkhoven m g parker creb-binding protein histone acetyltransferases nuclear proteins / chemistry nuclear receptor coactivator 1 nuclear receptor coactivator 2 nuclear receptor interacting protein 1 cytoplasmic and nuclear / chemistry estrogen / chemistry estrogen / metabolism recombinant fusion proteins / chemistry trans-activators* transcription factors / chemistry