Quantitative autoradiography of [3H]muscimol binding in rat brain
Abstract
A simple quantitative autoradiographic technique for the study of neurotransmitter receptors that includes the use of a tritium-sensitive film permits saturation, kinetic, and competition studies of brain samples as small as 0.01 cubic millimeter. This technique was used to study [3H]muscimol bindin …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
P.H.S.
Rats
Receptors
brain / drug effects
kinetics
brain / metabolism*
tritium
pmid:6272394
doi:10.1126/science.6272394
j b penney
h s pan
g w dauth
autoradiography
kainic acid / pharmacology
muscimol / metabolism*
oxazoles / metabolism*
drug / metabolism*
gaba-a
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265663
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