Low blood CD8+ T-lymphocytes and high circulating monocytes are predictors of HIV-1-associated progressive encephalopathy in children
Abstract
HIV-1 infection of the central nervous system (CNS) remains an important clinical concern. The first step toward PE prevention in HIV-1-infected children should be directed at predicting risk of PE and thus the prompt and reliable identification of infants who are at risk for CNS disease progression …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
Infant
Comparative Study
risk factors
Retrospective Studies
survival rate
predictive value of tests
leukocyte count
antiretroviral therapy
viral load
biomarkers / blood
age of onset
cd4-cd8 ratio
monocytes / drug effects
lymphocyte count
highly active
pmid:12563091
doi:10.1542/peds.111.2.e168
silvia sánchez-ramón
josé ma bellón
ma angeles muñoz-fernández
aids dementia complex / blood*
aids dementia complex / drug therapy
aids dementia complex / mortality
aids dementia complex / pathology*
cd4-positive t-lymphocytes / drug effects
cd4-positive t-lymphocytes / pathology
cd8-positive t-lymphocytes / drug effects
cd8-positive t-lymphocytes / pathology*
monocytes / pathology*
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261132
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