Inaccuracy of the log-rank approximation in cancer data analysis.

Inaccuracy of the log-rank approximation in cancer data analysis.

Rappoport, Nimrod;Shamir, Ron;
molecular systems biology 2019 Vol. 15 pp. e8754
238
rappoport2019inaccuracymolecular

Abstract

The log-rank test statistic is very broadly used in biology. Unfortunately, P-values based on the popular chi-square approximation are often inaccurate and can be misleading.

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