palliative benefits of the multimodality approach in the re-treatment of recurrent malignant glioma: two case reports

;T R Arulponni;M G Janaki;S Nirmala
Öneri 2009 Vol. 15 pp. 159-161
339
arulponni2009indianpalliative

Abstract

Two young male patients treated seven and four years back, for malignant glioma, returned with recurrence at the same site, with a World Health Organization (WHO) Performance Score of four and two. Both underwent resurgery and received postoperative reirradiation of 5040 cGy in 28 fractions and concurrent Temozolomide 75 mg/m 2 body surface area (BSA) daily, and one patient received additional adjuvant Temozolomide 250 mg (150 mg/m 2 BSA). Both patients tolerated the treatment well with 16 and 14 months follow-up from the time of recurrence. They were symptom-free, with normal physical function and good mental state, and resumed their respective jobs.

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