Primary Lymphoepithelial Carcinoma of the Submandibular Gland in A Young Patient: A Case Report.

Primary Lymphoepithelial Carcinoma of the Submandibular Gland in A Young Patient: A Case Report.

Ishak, Azlan Iskandar;Kong, Lai Shau;Yunus, Mohd Razif Md;Bakar, Mohd Zulkiflee Abu;
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India 2023 Vol. 75 pp. 2577-2580
49
ishak2023primaryindian

Abstract

Lymphoepithelial carcinoma (LEC) is a rare entity of malignancy. It has been associated with Epstein-Barr virus (EBV), and in regions where it is endemic, such as Southeast Asia, EBV is typically associated with nasopharyngeal carcinoma. The incidence of such malignancies in the young population is unusual. Here we report a 17-year-old with a 5-year history of a painless right submandibular mass presenting with a sudden increase in size for one month before surgery. Neck examination revealed a firm right submandibular gland measuring five by five cm, with an irregular surface, non-tender with normal overlying skin. We performed a fine needle aspiration cytology (FNAC), and he underwent computed tomography (CT) scan of the neck. He underwent a right submandibulectomy. Lymph nodes from levels I and II were also removed. The final histopathology was reported as LEC. Following this tissue diagnosis, another follow-up surgery, a modified radical neck dissection, was carried out for locoregional clearance. Postoperatively, he completed chemoradiotherapy treatment and is now on regular follow-up.

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