Alterations in the relative amounts of specific mRNA species in the developing human brain in Down's syndrome
Abstract
Total cellular polyadenylated RNA [poly(A)+ RNA] was prepared after guanidinium thiocyanate extraction of frozen brain tissue from age-matched normal and Down's-syndrome (trisomy 21) human foetuses. Poly(A)+ RNA populations were analysed by translation in vitro, followed by two-dimensional gel analy …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
RNA
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
protein biosynthesis
electrophoresis
brain / metabolism*
messenger / metabolism*
centrifugation
polyacrylamide gel
microtubules / metabolism
pmid:6204644
pmc1153608
doi:10.1042/bj2200179
s a whatley
c hall
l lim
brain / embryology
density gradient
down syndrome / embryology
down syndrome / metabolism*
endopeptidases
fetal proteins / metabolism
photofluorography
poly a / metabolism
rna / metabolism
serine endopeptidases*
Citation
ID:
266679
References
Blockchain Verification
Account:
NFT Contract Address:
0x95644003c57E6F55A65596E3D9Eac6813e3566dA
Article ID:
266679
Unique Identifier:
Network:
Scimatic Chain (ID: 481)
Loading...
Blockchain Readiness Checklist
Authors
Abstract
Journal Name
Year
Title
Creates 1,000,000 NFT tokens for this article
Token Features:
- ERC-1155 Standard NFT
- 1 Million Supply per Article
- Transferable via MetaMask
- Permanent Blockchain Record
Scan with Saymatik Web3.0 Wallet