Diagnosis of Streptococcus pneumoniae meningitis by polymerase chain reaction amplification of the gene for pneumolysin
Abstract
Diagnosis of bacterial meningitis has long been based on classical methods of Gram stain, serological tests, and culture of cerebrospinal fluid (CSF). The performance of these methods, especially culture and direct smear is thwarted by failure to detect bacteria following administration of antimicro …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
adult
female
male
adolescent
aged
middle aged
Child
Infant
preschool
DNA
sensitivity and specificity
Evaluation Study
pneumococcal / diagnosis*
meningitis
streptococcus pneumoniae / genetics
predictive value of tests
pneumococcal / cerebrospinal fluid
bacterial proteins / genetics
immunoenzyme techniques
streptolysins / genetics*
culture techniques
polymerase chain reaction*
pmid:17072463
doi:10.1590/s0074-02762006000500014
juliana de a matos
danielle j madureira
david e barroso
bacterial / cerebrospinal fluid*
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Citation
ID:
115704
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