Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

Ge Z;Leighton JS;Wang Y;Peng X;Chen Z;Chen H;Sun Y;Yao F;Li J;Zhang H;Liu J;Shriver CD;Hu H; ;Piwnica-Worms H;Ma L;Liang H;;
Cell reports 2018 Vol. 23 pp. -
475
z2018cellintegrated

Abstract

Protein ubiquitination is a dynamic and reversible process of adding single ubiquitin molecules or various ubiquitin chains to target proteins. Here, using multidimensional omic data of 9,125 tumor samples across 33 cancer types from The Cancer Genome Atlas, we perform comprehensive molecular charac …

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