RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids
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RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids

Ho-Su Sin, Artem Barski, Fan Zhang, Andrey V. Kartashov, Andre Nussenzweig, Junjie Chen, Paul R. Andreassen, Satoshi H. Namekawa;Ho-Su Sin;Artem Barski;Fan Zhang;Andrey V. Kartashov;Andre Nussenzweig;Junjie Chen;Paul R. Andreassen;Satoshi H. Namekawa;
genes & development 2012 Vol. 26 pp. 2737-
148
namekawa2012genesrnf8

Abstract

Sex chromosomes are uniquely subject to chromosome-wide silencing during male meiosis, and silencing persists into post-meiotic spermatids. Against this background, a select set of sex chromosome-linked genes escapes silencing and is activated in post-meiotic ...

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DOI:
10.1101/gad.202713.112
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC353307...

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