The mechanism and regulation of deadenylation: identification and characterization of Xenopus PARN.

The mechanism and regulation of deadenylation: identification and characterization of Xenopus PARN.

P R Copeland, M Wormington;P R Copeland;M Wormington;
rna 2001 Vol. 7 pp. 875-
132
wormington2001rnathe

Abstract

In Xenopus oocytes, the deadenylation of a specific class of maternal mRNAs results in their translational repression. Here we report the purification, characterization, and molecular cloning of the Xenopus poly(A) ribonuclease (xPARN). xPARN copurifies ...

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272216
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10.1017/s1355838201010020
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