The mechanism and regulation of deadenylation: identification and characterization of Xenopus PARN.
P R Copeland, M Wormington;P R Copeland;M Wormington;
rna2001Vol. 7pp. 875-
132
wormington2001rnathe
Abstract
In Xenopus oocytes, the deadenylation of a specific class of maternal mRNAs results in their translational repression. Here we report the purification, characterization, and molecular cloning of the Xenopus poly(A) ribonuclease (xPARN). xPARN copurifies ...