The objective of this study was to assess the effect of selected pesticides [herbicides (metribuzin and glyphosate), insecticides (imidacloprid and thiamethoxam) and fungicides (hexaconazole, metalaxyl and kitazin)] at recommended and higher dose rates on plant growth promoting activities of the Mesorhizobium sp. isolated from chickpea-nodules. A total of 50 rhizobial strains recovered from the nodules of chickpea root systems were identified following morphological, biochemical and host-specificity tests and tested for pesticide-tolerance. Among these strains, the Mesorhizobium sp. strain MRC4 was specifically selected due to the highest tolerance levels for all selected pesticides and the maximum production of plant growth promoting substances. Strain MRC4 produced indole acetic acid (44 μg ml−1), siderophores [salicylic acid (35 μg ml−1) and 2,3-dihydroxy benzoic acid (19 μg ml−1)], exo-polysaccharides (21 μg ml−1), HCN and ammonia. Under pesticide-stress, pesticide-concentration dependent progressive-decline in all plant growth promoting traits of the Mesorhizobium sp. strain MRC4 exposed was observed except for exo-polysaccharides which consistently increased with exceeding the concentration of each pesticide from recommended dose. For instance, hexaconazole at three times the recommended dose elicited the maximum stress on siderophore-biosynthesis by the Mesorhizobium sp. strain MRC4 and decreased salicylic acid and DHBA by 40% and 47%, respectively and the greatest stimulatory effect on exo-polysaccharides secretion was shown by imidacloprid which stimulated the Mesorhizobium sp. strain MRC4 to secrete EPS by 38%, compared to control. Generally, the maximum toxicity to plant growth promoting traits of Mesorhizobium was shown by glyphosate, thiamethoxam and hexaconazole, at three times the recommended rate among herbicides, insecticides and fungicides, respectively. This study revealed an additional aspect of the toxicological mechanisms of the pesticides through which they suppress the plant growth.