Esculetin from Fraxinus rhynchophylla attenuates atopic skin inflammation by inhibiting the expression of inflammatory cytokines
Abstract
Atopic dermatitis (AD) is a common chronic inflammatory skin disorder afflicting from infancy to adults with itching, scratching, and lichenification. We aimed to investigate the effects of esculetin from Fraxinus rhynchophylla on atopic skin inflammation. For induction of atopic skin inflammation, …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
female
Antigens
cell line
Inbred BALB C
anti-inflammatory agents / therapeutic use*
pmid:29656211
doi:10.1016/j.intimp.2018.04.005
na-hee jeong
eun-ju yang
sang-hyun kim
anti-inflammatory agents / pharmacology*
dermatophagoides
cytokines / antagonists & inhibitors*
cytokines / genetics
cytokines / immunology
dermatitis
allergic contact / drug therapy*
allergic contact / immunology
allergic contact / metabolism
dinitrochlorobenzene
fraxinus
keratinocytes / drug effects
keratinocytes / metabolism
nf-kappa b / metabolism
stat1 transcription factor / metabolism
skin / drug effects
skin / immunology
umbelliferones / pharmacology*
umbelliferones / therapeutic use*
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116407
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