Potent inhibition of respiratory syncytial virus by polyoxometalates of several structural classes
Abstract
A series of polyoxometalates (POM) were synthesized and evaluated for anti-respiratory syncytial virus (RSV) activity. POM containing zirconium, tungsten, silicon, platinum, niobium or germanium of a variety of structural types have been evaluated. Sixteen of the compounds had very striking anti-RSV …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
non-p.h.s.
P.H.S.
Cultured
cell line
cattle
respiratory syncytial viruses / drug effects*
antiviral agents / pharmacology*
respiratory syncytial viruses / physiology
cell survival / drug effects
tumor cells
pmid:9107383
doi:10.1016/s0166-3542(96)01019-4
d l barnard
c l hill
r f schinazi
cytopathogenic effect
viral / drug effects
respiratory syncytial viruses / pathogenicity
virus replication / drug effects
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114749
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