The interdigital glands of sheep perform various functions including those pertaining to sexual behaviors. Morphological and histological structure of the gland demonstrates differences among species. The aim of this study is to examine the morphological and histological structure of Hasak and Hasmer sheep's interdigital glands and to determine the differences with other sheep breeds. For this research, we selected 7 Hasak and 7 Hasmer female sheep. After scarification, the feet were obtained and used for anatomical and histological examinations. For the histological examination, the interdigital gland tissues were stained with Crossman modified triple, Periodic acid Schiff (PAS) and Alcian blue (AB) staining. The morphometric analysis results, mean values of weight, body length, body diameter, flexura, ductus length, ductus diameter, were observed as 0.80mm, 14.61mm, 5.98mm, 5.62mm, 26.58mm and 3.25mm respectively in Hasak and 0.8mm, 15.46mm, 6.37mm, 5.70mm, 24.52 and 3.52 in Hasmer sheep. The histochemical staining revealed that the apocrine secretion of this gland was PAS positive and AB negative. The weight, body length, body diameter, flexura, ductus length and ductus diameter in the forefoot's interdigital glands of both Hasak and Hasmer sheep were higher in a statistically significant manner than those of the hindfeet's glands.