Evaluation of obstetric outcomes and prognostic significance of graft function in kidney transplant recipient pregnancies.
Madazlı, Riza;Kaymak, Didem;Alpay, Verda;Erenel, Hakan;Dincer, M Tamer;Seyahi, Nurhan;
hypertension in pregnancy2020pp. 1-6
204
madazli2020evaluationhypertension
Abstract
: To evaluate obstetric and kidney outcomes in pregnancies with kidney transplantation.: We retrospectively reviewed 32 singleton pregnancies in kidney transplant recipients. Obstetric outcomes were explored according to the estimated glomerular filtration rates (eGFR) of patients.: The incidences of fetal growth restriction, preeclampsia were 18.8% and 34.4%, respectively. There was a significant negative correlation between first-trimester eGFR and perinatal mortality (r = -0.546, p = .0.001) and composite adverse obstetric outcome (r = -0.415, p = .0.018).: The degree of transplanted kidney function impairment at the beginning of pregnancy is the major determinant of pregnancy outcome.