An efficient one-pot synthesis of polyhydroquinolines at room temperature using HY-zeolite.
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An efficient one-pot synthesis of polyhydroquinolines at room temperature using HY-zeolite.

Das, Biswanath;Ravikanth, Bommena;Ramu, Ravirala;Vittal Rao, Bommena;
Chemical & pharmaceutical bulletin 2006 Vol. 54 pp. 1044-5
304
das2006anchemical

Abstract

An efficient one-pot synthesis of polyhydroquinolines by four-component coupling reactions of aldehydes, ethyl acetoacetate, dimedone and ammonium acetate in the presence of HY-zeolite at ambient temperature has been achieved. The conversions took shorter times to form the products in excellent yields. HY-zeolite can be recovered and reused.

Keywords

Antimicrobial activity multicomponent reaction antimalarial activity 5-imidazopyrazole incorporated polyhydroquinolines antituberculosis activity

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