In light of the labor conditions defined within the framework of neoliberalism implemented in Mexico, labor dynamics are problematized, the main problems of access to the health and social security system are identified and the systematic violation of rights - especially the right to work, to social security and to health - are discussed. The objective of this article is to contribute with proposals for the construction of a comprehensive, inclusive, healthcare and social security system that contributes to the improvement of the lives of workers.