Cryptogenic Organising Pneumonia As The Initial Presenting Manifestation of SLE

Cryptogenic Organising Pneumonia As The Initial Presenting Manifestation of SLE

, Neena Mampilly;, G Manoj;Paul, Binoy J;
bmh medical journal 2015 Vol. 2 pp. 79-83
247
2015cryptogenicbmh

Abstract

Cryptogenic Organising Pneumonia (COP), also called idiopathic Bronchiolitis Obliterans Organising Pneumonia( BOOP), is a distinct entity among the idiopathic interstitial pneumonias defined histopathologically by intraalveolar buds of granulation tissue. The etiology includes idiopathic, infectious, drug induced radiation induced and connective tissue diseases. Organising pneumonia occurs particularly in patients with dermatomyositis-polymyositis where it may be the presenting manifestation, and rarely in SLE, rheumatoid arthritis, scleroderma and other connective tissue diseases. We describe a 30 yr old lady who initially presented with respiratory symptoms, not responding to antibiotics. She was subsequently diagnosed as SLE and HRCT thorax showed consolidation involving both lung fields. A percutaneous lung biopsy revealed features of Cryptogenic Organising Pneumonia.

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