Synthesis of 6H-indolo[2,3-b]quinoxaline-N-glycosides and their cytotoxic activity against human ceratinocytes (HaCaT).
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Synthesis of 6H-indolo[2,3-b]quinoxaline-N-glycosides and their cytotoxic activity against human ceratinocytes (HaCaT).

Driller, Katrin Marie;Libnow, Stefanie;Hein, Martin;Harms, Manuela;Wende, Kristian;Lalk, Michael;Michalik, Dirk;Reinke, Helmut;Langer, Peter;
Organic & biomolecular chemistry 2008 Vol. 6 pp. 4218-23
211
driller2008synthesisorganic

Abstract

N-glycosides of 6H-indolo[2,3-b]quinoxalines were prepared and structurally characterized. The synthesis relies on the cyclocondensation of isatine-N-glycosides with 1,2-diaminobenzenes. Some products exhibit weak cytotoxic activity against human ceratinocytes (HaCaT).

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DOI:
10.1039/b812308j

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ID: 31328
Ref Key: driller2008synthesisorganic
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