Gastric cancer, inflammatory bowel disease and polyautoimmunity in a 17-year-old boy: CTLA-4 deficiency successfully treated with Abatacept
Abstract
Gut involvement is frequent in immunologic disorders, especially with inflammatory manifestations but also with cancer. In the last years, advances in functional and genetic testing have improved the diagnostic and therapeutic approach to immune dysregulation syndromes. CTLA-4 deficiency is a rare d …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
covid-19
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
male
case reports
adolescent
asymptomatic infections
pmid:34034269
doi:10.1097/meg.0000000000002185
giulia angelino
cristina cifaldi
andrea finocchi
abatacept / therapeutic use*
autoimmune diseases* / diagnosis
autoimmune diseases* / drug therapy
autoimmune diseases* / genetics
ctla-4 antigen / deficiency*
ctla-4 antigen / genetics
inflammatory bowel diseases* / diagnosis
inflammatory bowel diseases* / drug therapy
inflammatory bowel diseases* / genetics
stomach neoplasms* / diagnosis
stomach neoplasms* / drug therapy
stomach neoplasms* / genetics
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284142
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