The thesis discusses topics related to the development of business process management systems. Business process management systems have evolved on the basis of workflow management systems through incremental inclusion of standard information system functions, for example, resource and client management. The application of model driven development is required to deal with the complexity of business management systems and to increase development efficiency. In contrast to conventional information systems, the behavior of business management systems is strongly affected by the business models that they execute. Thus, business process models also can be used for designing and developing business management systems using sequentially applied model transformations that adapt models to a specific execution platform.