Climate change is set to be particularly disruptive in poor agricultural communities. This study examines the effects of, and farmer’s perceptions of, climate change on farming practices for cassava and maize in Lagos, Nigeria. Analysis of weather data from 1998 to 2018 (the most recent available) reveals little impact on cassava yield but a significant impact on maize yield. Furthermore, survey results indicate that farmers in this area are currently implementing techniques to adapt to changes in climate based on the type of crop grown. Agriculture in Lagos, Nigeria, is largely rain-fed and climate change negatively impacts crop productivity by decreasing crop yield and soil fertility, limiting the availability of soil water, increasing soil erosion, and contributing to the spread of pests. A decline in crop production due to climate change may be further exasperated by a lack of access to farming technology that reduces over-reliance on the rain-fed farming system and subsistence agriculture. This study indicates that there is a need for initiatives to motivate young and older farmers through access to credits, irrigation facilities, and innovative climate change adaptive strategies.